Native Human Cathepsin B, Liver

Molecule:

Cathepsin B

Synonyms:

Cathepsin B, APP secretase, APPS, cathepsin B1

Species:

Human

Cat. No.:

CSI19792A pdf (datasheet)

Quantity/Size:

25 μg

Price:

$400.00 BUY

Description:

Cathepsin B, a cysteine proteinase, is located in lysosomes and is involved in tissue degradation and restructuring. Specifically, cathepsin B is believed to be involved in the intracellular digestion of extracellular proteins taken up by endocytosis.

Concentration:

≥ 1.0 mg/ml, lot specific

Entrez Symbol:

CTSB

Uniprot Name:

Cathepsin B

Uniprot ID:

P07858

Data PDF:

CSI19792

Source:

Human liver

Molecular Weight:

27.5 kDa

Formulation:

50 mM Sodium Acetate, 1 mM EDTA, pH 5.0.

Purity:

>95% by SDS-PAGE analysis

Biological Activity:

One unit is defined as the amount of enzyme that hydrolyzes one µmole of Z-Arg-Arg-beta-naphthylamide per minute at 40°C, using 100 mM Na/K phosphate, pH 6.0, with 1.33 mM EDTA and 2 mM DTT as the activation buffer.

Specific Activity:

≥ 200 units/mg.

Storage/Stability:

Store at -80°C for up to 1 year. Upon initial thaw, prepare working aliquots and store at -80°C. Avoid repeated freeze-thaw cycles.