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  • Mouse Anti-Human VEGFR-2/KDR (Clone #EIC) Biotin mAb

Mouse Anti-Human VEGFR-2/KDR (Clone #EIC) Biotin mAb

Molecule:

VEGFR-2/KDR

Synonyms:

Vascular endothelial growth factor receptor 2, VEGFR-2, Kinase insert domain receptor, KDR, Fetal liver kinase 1, FLK-1, CD309

Species:

Human

Cat. No.:

CMV002BT pdf (datasheet)

Quantity/Size:

50 μg

Price:

$770.00 BUY

Description:

VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

Entrez Symbol:

KDR

Uniprot Name:

Vascular endothelial growth factor receptor 2

Uniprot ID:

P35968

Data PDF:

CMV002BT

Specificity:

Human VEGFR-2

Host Species:

Mouse

Immunogen:

Recombinant human soluble extracellular KDR (110 kDa)

Isotype:

IgG1

Clone:

#EIC

Conjugate:

Biotin

Formulation:

Lyophilized from PBS, containing 50x BSA and 0,02% sodium azide

Purification:

Protein G Chromatography

Application:

ELISA, FC, IF, IHC, WB

Application notes:

Western blot: use at 2-5 µg/ml
ELISA: use at 1-10 µg/ml
FACS: use at 2-10 µg/ml
IF/IHC: use at 6-30 µg/ml

Storage/Stability:

Store at -20°C to -80°C for at least 1 year.