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Mouse Anti-Human VEGFR-2/KDR Clone #3(4H3) Biotin mAb

Molecule:

VEGFR-2/KDR

Synonyms:

FLK1, CD309, VEGFR, VEGFR2

Species:

Human

Cat. No.:

CMV012BT pdf (datasheet)

Quantity/Size:

50 μg

Price:

$570.00 BUY

Description:

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. VEGF recptor 2 is one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signaling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, and T-cell protein tyrosine phosphatase.

Data PDF:

CMV012BT

Specificity:

Detects Native Human KDR/VEGFR-2 on the surface of different human cell types.

Host Species:

Mouse

Immunogen:

Recombinant Human soluble extracellular KDR (D7)

Isotype:

IgG1

Clone:

#3(4H3)

Conjugate:

Biotin

Formulation:

Lyophilized from a 0.2 µm sterile filtered 0.1M Tris-Cl, 0.2M NaCl, 0.02% NaN3 buffer solution (pH 7.4), containing 50 µg BSA per 1 µg antibody.

Purification:

Protein G chromatography

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water for a concentration of 0.1 -1.0 mg/ml.

Application notes:

FACS: suggested concentration 2-5 μg/ml.
Optimal dilution should be determined by each laboratory for each application.

Storage/Stability:

Store lyophilized at -20°C for up to 1 year. Following reconstitution, stable for at least two weeks at 2-8°C or at least 6 months when stored at -20°C. Avoid repeated freeze-thaw cycles.