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Mouse Anti-Human Galectin-8 (Clone B-Z18) mAb

Synonyms:

LGALS8, GAL-8, PCTA-1

Species:

Human

Cat. No.:

CDM554 pdf (datasheet)

Quantity/Size:

200 tests

Price:

$320.00 BUY

Description:

Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium, and to restrict infection of Picornaviridae viruses. Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.

Entrez Symbol:

LGALS8

Uniprot Name:

Galectin-8

Uniprot ID:

O00214

Data PDF:

CDM554

Specificity:

Recognizes both native and recombinant Galectin-8

Host Species:

Mouse

Immunogen:

Recombinant human Galectin-8

Isotype:

IgG2a kappa light chain

Clone:

B-Z18

Formulation:

Sterile-filtered PBS, 1% BSA, 0.09% sodium azide

Application:

FC

Application notes:

Flow cytometry: Use 10 μl to label 10e6 cells or 100 μl of whole blood

Storage/Stability:

Store at 2-8°C.