• Home /
  • Mouse Anti-Human CXCR2/ IL-8 Receptor B mAb

Mouse Anti-Human CXCR2/ IL-8 Receptor B mAb

Synonyms:

C-X-C chemokine receptor type 2, CXC-R2, CXCR-2, CDw128b, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8R B, IL-8 receptor type 2, CD182

Species:

Human

Cat. No.:

CMH011 pdf (datasheet)

Quantity/Size:

50 µg

Price:

$900.00 BUY

Concentration:

1 mg/ml

Description:

Human CXCR2/ IL-8 Receptor B (IL-8RB), is a member of the G-protein-coupled receptor family. CXCR2/ IL-8RB is a receptor for interleukin 8 (IL-8), which it binds with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to CXCL1/ MGSA, a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serumdependent melanoma cell growth. CXCR2/ IL-8RB mediates neutrophil migration to sites of inflammation and mediates the angiogenic effects of IL-8 in intestinal microvascular endothelial cells.

Uniprot Name:

C-X-C chemokine receptor type 2

Uniprot ID:

P25025

Data PDF:

CMH011

Specificity:

Human IL-8RB

Host Species:

Mouse

Immunogen:

L1.2 cells expressing IL - 8 Receptor B (Human)

Isotype:

IgG1

Formulation:

PBS

Purification:

Protein G affinity chromatography

Application:

FC, IHC

Application notes:

IHC: recommended concentration 5 µg/ml, or frozen tissues at 1:10 to 1:20.

Storage/Stability:

Store at 2-8°C or in aliquots at -20°C. Avoid repeated freeze-thaw cycles.