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Mouse Anti-Human CD146 / MUC18 (Clone B-T46) mAb

Synonyms:

Cell surface glycoprotein MUC18, Melanoma-associated antigen MUC18, Melanoma cell adhesion molecule, MCAM, CD146

Species:

Human

Cat. No.:

CDM561 pdf (datasheet)

Quantity/Size:

200 tests

Price:

$320.00 BUY

Description:

CD146 is a 118 kD integral transmembrane glycoprotein also known as MUC18, S-Endo, MCAM, and Mel-CAM (melanoma cell adhesion molecule). It belongs to the immunoglobulin superfamily. CD146 is expressed on melanoma cells, epithelial cells, endothelial cells, fibroblasts, activated T cells, multipotent mesenchymal stromal cells, and activated keratinocytes. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration.

Entrez Symbol:

MCAM

Uniprot Name:

Cell surface glycoprotein MUC18

Uniprot ID:

P43121

Data PDF:

CDM561

Specificity:

Recognizes native and recombinant human CD146

Host Species:

Mouse

Immunogen:

Recombinant human CD146

Isotype:

IgG1 Kappa light chain

Clone:

B-T46

Formulation:

Sterile-filtered PBS, 1% BSA, 0.09% sodium azide

Application:

FC

Application notes:

Flow cytometry: Use 10 μl to label 10e6 cells or 100 μl of whole blood

Storage/Stability:

Store at 2-8°C. DO NOT FREEZE.