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Research Grade Tebentafusp

Synonyms:

Bispecific fusion protein, CAS: 1874157-95-5

Species:

Human

Cat. No.:

DHC27706B pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$1,970.00 BUY

Concentration:

1.0 mg/ml, lot specific

Description:

Research Grade Tebentafusp is a humanized bispecific, fusion protein which targets T-cell surface glycoprotein CD3 epsilon chain. This first-in-class drug of immune-mobilizing monoclonal T cell receptors against cancer (ImmTACs), a recently developed cancer immunotherapy with a novel mechanism of action. ImmTACs bind to target cancer cells that express a specific antigen of interest and recruit cytotoxic T cells to lyse the cells ( T cell engager.)

Entrez Symbol:

CD3E

Uniprot Name:

T-cell surface glycoprotein CD3 epsilon chain

Uniprot ID:

P07766

Data PDF:

DHC27706

Purity:

> 95% as determined by SDS-PAGE

Specificity:

Human T-cell surface glycoprotein CD3 epsilon chain (CD3e)

Formulation:

9 mM Citric acid monohydrate, 41 mM Na2HPO4, 1% mannitol, 5% trehalose,0.02% Tween20, 2mM DTT, pH6.5

Purification:

Nickel (IMAC) immobilized metal affinity chromatography

Storage/Stability:

Recommended storage, undiluted at 2-8°C for up to 1 week, or in working aliquots at -20°C to -80°C for up to 1 year. Avoid freeze/thaw cycles.