Research Grade Etokimab

Synonyms:

ANB020, CAS: 2022981-44-6,IL33

Cat. No.:

DHB74001A pdf (datasheet)

Quantity/Size:

100 ug

Price:

$380.00 BUY

Concentration:

1.0 mg/ml, lot specific

Description:

Research Grade Etokimab is a human monoclonal antibody which targets Interleukin-33. In peanut allergy, the body overreacts to peanuts as IL-33 activates an antibody called immunoglobin E. These antibodies cause allergic response such as mouth itchiness, hives, breathing difficulties and potentially fatal anaphylactic shock. ANB020, now called etokimab, is currently in phase 2a testing in eczema, which is also known as atopic dermatitis. Scientists from the Medical Research Council Human Immunology Unit at the University of Oxford released data from 12 patients showing that 83% who were treated with etokimab reported a reduction in disease severity after 29 days.

Uniprot Name:

Interleukin-33

Uniprot ID:

O95760

Purity:

95% as determined by SDS-PAGE

Specificity:

Human Interleukin-33

Isotype:

IgG1 Kappa light chain

Formulation:

0.01M PBS, pH 7.4

Purification:

Protein A/G affinity chromatography

Storage/Stability:

Recommended storage, undiluted at 2-8°C for up to 1 week, or in working aliquots at -20°C to -80°C for up to 1 year. Avoid freeze/thaw cycles.