Synonyms:
Transthyretin, Prealbumin, TBPA, TTR, PALB, ATTR, Transthyretin amyloidosis
Cat. No.:
DHK25501B
pdf (datasheet)
Concentration:
1.0 mg/ml, lot specific
Description:
Research Grade Coramitug is a chimeric monoclonal antibody affinity purified from cell culture supernatant. The investigational humanized monoclonal antibody coramitug was designed to target and clear the non-native transthyretin aggregates (misTTR depleter) associated with disease pathology that underlies both wtATTR and hATTR, without affecting the native, or normal tetrameric form of the protein (TTR).
Uniprot Name:
Transthyretin
Purity:
> 95% as determined by SDS-PAGE
Specificity:
Human Transthyretin
Isotype:
Chimeric IgG1-kappa
Formulation:
Sterile filtered 0.01M PBS, pH 7.4
Purification:
Protein A or G affinity chromatography from cell culture supernatant
Application:
FS , Functional assay
Storage/Stability:
Recommended storage, undiluted at 2-8°C for up to 1 week, or in working aliquots at -20°C to -80°C for up to 1 year. Avoid freeze/thaw cycles.
