Research Grade Anti-Human MET/c-Met/HGFR (CE-355621) mAb

Synonyms:

Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor (SF receptor), Tyrosine-protein kinase Met, CE-355621, CE 355621

Species:

Human

Cat. No.:

DHC34205B pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$1,715.00 BUY

Concentration:

1.0 mg/ml, lot specific

Description:

Research Grade Anti-Human MET/c-Met/HGFR (CE-355621) is a human monoclonal antibody that binds to the extracellular domain of proto-oncogene c-Met (HGFR.) The antibody antagonizes c-Met function by blocking the binding of the ligand HGF to c-Met and by blocking ligand-dependent c-Met activation, which subsequently induces internalization and downregulation of the receptor.

Entrez Symbol:

MET

Uniprot Name:

Hepatocyte growth factor receptor

Uniprot ID:

P08581

Data PDF:

DHC34205

Purity:

> 95% by SDS-PAGE

Specificity:

Human HGF receptor (Proto-oncogene c-Met)

Host Species:

Human

Isotype:

IgG

Clone:

CE-355621

Formulation:

0.01M PBS buffer, pH 7.4

Purification:

Protein A/G affinity chromatography from cell culture supernatant

Application:

FS , Functional assay

Storage/Stability:

Recommended storage, undiluted at 2-8°C for up to 1 week, or in working aliquots at -20°C to -80°C for up to 1 year. Avoid freeze/thaw cycles.