Recombinant Single Chain Cardiac Troponin I-C 2nd Generation

Synonyms:

Troponin I, cardiac muscle, Cardiac troponin I, Troponin C, slow skeletal and cardiac muscles, TN-C,

Species:

Human

Cat. No.:

CRT136A pdf (datasheet)

Quantity/Size:

2 μg

Price:

$450.00 BUY

Description:

Troponin Complex is a heteromeric protein playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, Troponin I, Troponin T and TroponinC. Each subunit is responsible for part of Troponin Complex function. E.g. Troponin I inhibits ATP-ase activity of acto-myosin.Troponin T and Troponin Iare presented in cardiac muscles in different forms than in skeletal muscles. Purified subunits of rcTnI, rcTnC and rcTnT are recomplexed in vitro under appropriate conditions.
Recombinant Single Chain Cardiac Troponin I-C 2nd generation produced in E. coli is a single, non-glycosylated, polypeptide chain (aa28-110-Linker-cTnC). 1mg of scIC2 is equivalent to 0.82mg of full length human cardiac TNI on a molar basis.

Entrez Symbol:

TNNI3, TNNC1

Uniprot Name:

Troponin I, cardiac muscle, Troponin C, slow skeletal and cardiac muscles

Uniprot ID:

P19429, P63316,

Data PDF:

CRT136

Source:

E. coli

Molecular Weight:

30 kDa (aa28-110-Linker-cTnC)

Formulation:

Sterile- filtered 20mM Tris-HCl, 250mM NaCl and 50% glycerol, pH 7.5.

Purity:

> 90% as determined by SDS-PAGE.