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Recombinant Rat Leptin Antagonist Triple Mutant PEG

Molecule:

Leptin

Synonyms:

Leptin, Obesity factor, OB

Species:

Rat

Cat. No.:

CS425A pdf (datasheet)

Quantity/Size:

5 μg

Price:

$450.00 BUY

Description:

Recombinant Rat Leptin Antagonist Triple Mutant is a single non-glycosylated polypeptide chain containing 146 aa with an additional Ala at the N-terminus and having a molecular mass of ~16 kDa. The mutant was produced by substitutions at L39A, D40A, and F41A.

To produce the pegylated protein, the mutant was bound to 20 kDa mono-PEG at the N-terminus, resulting in a 35.6 kDa protein. The Mutant PEG runs as a 48 kDa protein and was purified by proprietary chromatographic techniques.

Uniprot Name:

Leptin

Uniprot ID:

P50596

Data PDF:

CS425

Source:

E. coli

Molecular Weight:

36.5 kDa

Formulation:

Lyophilized from a concentrated (0.65 mg/ml) solution containing 0.003 mM NaHCO3.

Purity:

> 99.0% as determined by SEC-HPLC and SDS-PAGE analyses.

Biological Activity:

Inhibits leptin-induced proliferation of BAF/3 cells stably transfected with the long form of the human leptin receptor.

Storage/Stability:

Store below -20°C