Recombinant Rat IGF-I

Molecule:

IGF-I

Synonyms:

Insulin-like growth factor 1, Insulin-like growth factor I, IGF-I, Somatomedin

Species:

Rat

Cat. No.:

CRI117C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$1,445.00 / Special Price: $1,220.00 BUY

Description:

Insulin-like growth factor I (IGF-I) is a growth factor that is produced by the liver. IGF-I production is stimulated by growth hormone (GH). IGF-I binds the insulin-like growth factor I receptor (IGF-I receptor) and the insulin receptor to stimulate systemic body growth. IGF-I is one of the most potent activators of the AKT signaling pathway, which stimulates cell proliferation and inhibits programmed cell death. Mature human IGF-I shares 100% homology with bovine and porcine IGF-I.

Entrez Symbol:

Igf1

Uniprot Name:

Insulin-like growth factor 1

Uniprot ID:

P08025

Data PDF:

CRI117

Source:

E. coli

Molecular Weight:

7.7 kDa (70 aa) monomer

Physical State:

Lyophilized

Formulation:

Lyophilized from a 0.2 μm filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Purity:

>95% by reducing and non-reducing SDS-PAGE

Biological Activity:

ED50 is 51-85 ng/ml, determined by dose dependent proliferation of MCF-7 cells.

Endotoxin Level:

<0.05 EU/μg as determined by USP <85>/ EP 2.6.14

Amino Acid Sequence:

GPETLCGAEL VDALQFVCGP RGFYFNKPTG YGSSIRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPTKSA

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.