Recombinant Rat Protein Farnesyltransferase alpha and beta subunit, Active

Synonyms:

Type 1 geranylgeranyltransferase subunits alpha and beta, GGTase-I, FTase-alpha, beta, CAAX farnesyltransferase subunits alpha, beta

Species:

Rat

Cat. No.:

CSI13585 pdf (datasheet)

Quantity/Size:

50 μg

Price:

$740.00 BUY

Description:

FTase catalyzes the transfer of the farnesyl group from farnesyl diphosphate to proteins containing a C-terminal CaaX motif, where ’C’ is a conserved cysteine that is the site of farnesyl modification, ’a’ is usually an aliphatic amino acid, and ’X’ is methionine, serine, glutamine, or alanine.

Entrez Symbol:

Fnta/Fntb

Uniprot Name:

Type 1 geranylgeranyltransferase subunits alpha and beta

Uniprot ID:

Q04631, Q02293

Data PDF:

CSI13585

Source:

E. coli

Molecular Weight:

alpha-subunit: 44 kDa
beta-subunit: 49 kDa

Tag:

none

Formulation:

50 mM HEPES, pH 7.4, 40 mM NaCl, 1 mM TCEP, 5 μM ZnCl2

Purity:

> 90 % as determined by SDS-PAGE

Biological Activity:

1 pmol of FTase will transfer 1 pmol of farnesyl to H-Ras in 15 min at 37°C.

Storage/Stability:

Store at -80°C