• Home /
  • Recombinant Mouse IFN-gamma

Recombinant Mouse IFN-gamma

Molecule:

IFN-gamma

Synonyms:

IFN-g, Interferon-gamma, IFN-γ

Species:

Mouse

Cat. No.:

CRI001C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$1,205.00 BUY

Description:

Interferon-gamma (IFN-γ) is a cytokine produced primarily by T-lymphocytes and natural killer cells following antigen-specific activation. IFN-γ binds IFN-γ receptors (IFN-γ R1 and IFN-γ R2), which are expressed on most immune cells, to activate the JAK-STAT pathway. IFN-γ-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules. Mouse IFN-γ is not cross-reactive with human IFN-γ.

Entrez Symbol:

Ifng

Uniprot Name:

Interferon gamma

Uniprot ID:

P01580

Data PDF:

CRI001

Source:

E. coli

Molecular Weight:

15.7 kDa (134 aa), monomer

Formulation:

Lyophilized from a sterile-filtered aqueous solution containing 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5

Purity:

> 95% by reducing and non-reducing SDS-PAGE

Biological Activity:

< 1 ng/ml, by viral CPE assay using EMC virus on L929 cells.

Specific Activity:

> 1 x 106 U/mg

Endotoxin Level:

≤ 0.1 EU/µg of protein by kinetic LAL analysis.

Amino Acid Sequence:

MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year. Upon reconstitution, prepare working aliquots and store at -20°C to -80°C. It is recommended that a carrier protein such as 0.1% HSA or BSA is added for long term storage. Avoid repeated freeze-thaw cycles.