Recombinant Human RAF-1, Binding Domain (aa 50-132) GST-tag

Synonyms:

RAF proto-oncogene serine/threonine protein kinase, proto-oncogene c-RAF, cRaf

Species:

Human

Cat. No.:

CSI14590 pdf (datasheet)

Quantity/Size:

300 μg

Price:

$750.00 BUY

Description:

Raf is a member of the serine/threonine proteine kinase family involved in regulation of cell growth and differentiation and is the most important effector of Ras. Full-length Raf is composed of three conserved regions responsible for interaction with Ras, for phosphorylation and for catalytic activity. RafRBD (Ras binding domain, amino acids 50 -132) mediates interaction with membrane-anchored Ras necessary for activation of the kinase activity of Raf.

The GST-Tag facilitates the protein‘s application in typical GST pull-down assays.

Uniprot Name:

RAF proto-oncogene serine/threonine-protein kinase

Uniprot ID:

P04049

Data PDF:

CSI14590

Source:

E. coli

Molecular Weight:

9.4 kDa (amino acids 50 - 132)

Formulation:

PBS, pH 7.4

Purity:

> 95% by SDS-PAGE

Storage/Stability:

Store at -80°C for up to 1 year. Upon initial thaw, prepare aliquots and store at -80°C. Avoid freeze-thaw cycles.