Recombinant Human Platelet Factor 4

Synonyms:

Platelet factor 4, PF-4, C-X-C motif chemokine 4, Iroplact, Oncostatin-A

Species:

Human

Cat. No.:

CSI19812C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$1,620.00 BUY

Description:

Platelet Factor 4 is synthesized in megakaryocytes and platelets. Depending on the protein concentration and buffer conditions, PF4 appears as a mono-, di-, tri-, or tetramer. PF4 is biologically active in the tetrameric form, promotes blood coagulation and is also important in wound healing and inflammation. PF4, together with heparin (PF4-heparin complex) is an important antigen of antibodies inducing heparin-induced thrombocytopenia (HIT). Purified PF4 is used in several laboratory tests for the detection of HIT antibodies.

Entrez Symbol:

PF4

Uniprot Name:

Platelet factor 4

Uniprot ID:

P02776

Data PDF:

CSI19812

Source:

E. coli

Molecular Weight:

7.8 kDa monomer

Formulation:

Lyophilized from sterile filtered PBS, carrier free. HBSS and 1.6 M NaCl by request.

Purity:

>95% by SDS-PAGE, silver staining

Amino Acid Sequence:

MEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCP TAQLIATLKNGRKICLDLQAPLYKKIIKKLLES

Storage/Stability:

Store at -20°C to -80°C.