Recombinant Human Osteocrin (HEK)

Cat. No.:

CRO103B pdf (datasheet)

Quantity/Size:

100 μg

Price:

$1,880.00 BUY

Description:

Human osteocrin (OSTN), also called musclin, is a secreted protein that acts as an endogenous ligand for the natriuretic peptide receptor C (NPR-C). This mechanism has been linked to various physiological effects, including stimulation of bone growth by increasing C-type natriuretic peptide (CNP) availability, protection of the heart from damage, and potential roles in glucose metabolism and brain development.

Recombinant Human Osteocrin is comprised of 112 amino acid residues (28-133 a.a.) plus a 6 a.a. C-terminal His tag (underlined in a.a. sequence below).

Concentration:

0.5 mg/ml

Entrez Symbol:

OSTN

Uniprot Name:

Osteocrin

Uniprot ID:

P61366

Data PDF:

CRO103

Source:

HEK293 cells

Molecular Weight:

12.5 kDa

Tag:

C-terminal His

Formulation:

Sterile filtered PBS, pH 7.4, 50% glycerol

Purity:

>95% by SDS-PAGE

Biological Activity:

ED50 < 20 ng/ml determined by binding in a functional ELISA with Human natriuretic peptide receptor C

Amino Acid Sequence:

VDVTTTEAFD SGVIDVQSTP TVREEKSATD LTAKLLLLDE LVSLENDVIE TKKKRSFSGF GSPLDRLSAG SVDHKGKQRK VVDHPKRRFG IPMDRIGRNR LSNSRGHHHH HH  (C-terminal 6x His Tag underlined)

Storage/Stability:

Store at 2-8°C for immediate use (2-4 weeks.) For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) and store at -20 °C to -80°C. Avoid repeated freeze-thaw cycles.

Application:

Functional assay