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  • Recombinant Human MAPK11/p38 beta, Active

Recombinant Human MAPK11/p38 beta, Active

Species:

Human

Cat. No.:

CRP101A pdf (datasheet)

Quantity/Size:

5 μg

Price:

$350.00 BUY

Description:

MAPK11 is a member of the p38 MAP kinase family and is activated by both proinflammatory cytokines and environmental stress. The MAPK11 is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase. Alternatively spliced transcript variants encoding the same protein have been observed.

Concentration:

0.1 mg/ml

Entrez Symbol:

MAPK11

Uniprot Name:

Mitogen-activated protein kinase 11

Uniprot ID:

Q15759

Data PDF:

CRP101

Source:

Insect cells

Molecular Weight:

approximately 71 kDa

Tag:

N-terminal GST

Formulation:

50 mM Tris-HCl, 150 mM NaCl, 10 mM glutathoine, 0.25 mM DTT, 0.1 mM EDTA, 0.1 mM PMSF, 25% Glycerol, pH 7.5

Purity:

> 95% by SDS-PAGE (Coomassie)

Specific Activity:

> 500 nmol/min/mg:, by Kinase Specific Activity: nmol phosphate incorporated into the PKB-sub peptide (CKRPRAASFAE) per minute per mg protein at 30ºC for 15 minutes using a final concentration of 50 µM ATP (0.83 µCi/assay).

Storage/Stability:

Store in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.