Recombinant Human Interleukin-2 (HEK293) His Tag

Synonyms:

Interleukin-2, IL-2, T-cell Growth Factor, TCGF, Aldesleukin, Lymphokine

Species:

Human

Cat. No.:

CRI112A pdf (datasheet)

Quantity/Size:

25 μg

Price:

$450.00 BUY

Description:

Interleukin-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. The receptor for IL-2 contains three subunits (55 kDa IL2Rα, 75 kDa IL2Rβ, 64 kDa common gamma chain γc/IL2Rγ) that are present on the cell surface in varying preformed complexes.

Entrez Symbol:

IL2

Uniprot Name:

Interleukin-2

Uniprot ID:

P60568

Data PDF:

CRI112

Source:

HEK293 cells

Molecular Weight:

16.4 kDa predicted (Ala21-Thr153) monomer
17 & 18 kDa, apparent SDS-PAGE due to glycosylation

Tag:

C-terminal His

Formulation:

Lyophilized from sterile filtered PBS, pH 7.4 containing 1.8 mM Trehalose

Purity:

>90 % by SDS-PAGE

Biological Activity:

EC50 = 0.2 ng/ml, determined by the dose-dependent proliferation of Kit225 cells

Endotoxin Level:

Negative by cell based assay

Storage/Stability:

Store at -80°C up to 1 year