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Recombinant Human Interferon alpha 2a

Molecule:

IFN-alpha 2a

Synonyms:

IFNA, INFA2, interferon alpha-2, leIF A, IFN-alpha-2, interferon alpha A, interferon alpha- A, alpha-2a interferon

Species:

Human

Cat. No.:

CRH063A pdf (datasheet)

Quantity/Size:

20 µg

Price:

$110.00 BUY

Description:

Interferon-alpha 2a (IFN-α2a) is a type I interferon made by leukocytes during viral infection. The JAK-STAT pathway mediates the antiviral and anti-cell proliferation activities of IFN-α2a. IFN-α proteins are widely used as standard treatments during antiviral and antineoplastic therapies. The IFN-α2a variant differs from IFN-α2b by one amino acid.

Entrez Symbol:

IFNA2

Uniprot Name:

Interferon alpha-2

Uniprot ID:

P01563

Data PDF:

CRH063

Source:

E. coli

Molecular Weight:

19.4 kDa (166 aa) monomer

Formulation:

Lyophilized from a sterile-filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA).

Purity:

> 95% by SDS-PAGE

Biological Activity:

ED50 < 0.005 ng/ml, determine by viral cytopathic effect (CPE) bioassay using EMC virus on A549 cells.

Specific Activity:

> 2.0 x 108 U/mg

Endotoxin Level:

≤1 EU/µg of protein by kinetic LAL analysis

Amino Acid Sequence:

MCDLPQTHSL GSRRTLMLLA QMRKISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1 mg/ml. DO NOT VORTEX. Allow several minutes for complete reconstitution. Further dilutions should be made in appropriate buffered solutions.

Storage/Stability:

Store at -20°C to -80°C for up to 1 year.