Recombinant Human IL-1 alpha

Molecule:

IL-1 alpha

Synonyms:

Interleukin 1-alpha, IL-1A, IL1, IL1F1

Species:

Human

Cat. No.:

CRI136B pdf (datasheet)

Quantity/Size:

100 μg

Price:

$1,400.00 BUY

Description:

Interleukin-1 alpha is a proinflammatory cytokine produced by a wide variety of cell types, including macrophages, osteoblasts, monocytes, and hepatocytes. Circulating levels are normally low and only rise after stimulation by agents such as those produced by inflammation, infection, or microbial endotoxins. IL-1 alpha possesses a wide variety of biological activities and exerts its effects by binding to specific cell surface receptors.

Entrez Symbol:

IL1A

Uniprot Name:

Interleukin 1-alpha

Uniprot ID:

P01583

Data PDF:

CRI136

Source:

E. coli

Molecular Weight:

~18.0 kDa (159 aa) monomer

Formulation:

Lyophilized from sterile filtered PBS, pH 7.4

Purity:

> 97% by SDS-PAGE and HPLC

Biological Activity:

ED50 < 1.0 pg/ml, determined by dose-dependent cell proliferation assay using murine D10S cells.

Specific Activity:

> 1.0 × 10e9 U/mg

Endotoxin Level:

< 1.0 EU/μg as determined by LAL method.

Amino Acid Sequence:

SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA

Storage/Stability:

Store at -20°C to -80°C.