GDNF

hGDNF, astrocyte-derived trophic factor, ATF1, ATF2

Human

CRG400C-AF pdf (datasheet)

1.0 mg

$6,265.00 / Special Price: $5,380.00 BUY

Glial Cell line-Derived Neurotrophic Factor (GDNF) is a neurotrophic factor that is closely related to other neurotrophic factors, such as Neurturin, Persephin, and Artemin, by a common structural feature called the cysteine-knot. GDNF signals through a multicomponent system of receptors that includes RET and GFRα1-4, to promote dopamine uptake, survival and differentiation of neurons.
Made without animal-derived components in an animal-free facility.

GDNF

Glial cell line-derived neurotrophic factor

P39905

CRG400-AF

E. coli

Homodimer, 15.2/30.4 kDa (135/270 aa)

Lyophilized from a sterile filtered solution in 10 mM sodium citrate, 100 mM sodium chloride, pH 4.0

≥95% by reducing and non-reducing SDS-PAGE

ED₅₀ < 3.0 µg/ml, determined by the dose-dependent proliferation of C6 cells

≤ 0.1 EU/µg by kinetic LAL

Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1 mg/mL. DO NOT VORTEX. Allow several minutes for complete reconstitution.

Upon receipt, store as supplied at -20°C to -80°C for up to one year. Upon reconstitution, the preparation is stable for up to 1 month at 2-8 °C, 3 months at -20°C to -80°C. For long term storage dilute to working aliquots containing 0.1% BSA and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.