Synonyms:
Granulocyte colony-stimulating factor, G-CSF, Pluriprotein, Filgrastim, Lenograstim, CSF3
Description:
Granulocyte Colony Stimulating Factor is a growth factor and/or cytokine produced by the endothelium, macrophages and a number of other immune cells. GCSF stimulates the bone marrow to produce granulocytes and also to stimulate the survival, p
Uniprot Name:
Granulocyte colony-stimulating factor
Physical State:
Lyophilized
Formulation:
Lyophilized from 1 mg/ml sterile-filtered 10 mM HCl, pH 6.5 containing 0.4mg Tween-20, 100mg mannitol, 160mg L-arginine, 40mg phenylalanine and 4mg methionine.
Purity:
>98% by SDS-PAGE and HPLC analyses.
Biological Activity:
ED50 < 0.1 ng/ml, by the dose-dependant proliferation of murine NFS-60 cells (measured by 3H-thymidine uptake)
Amino Acid Sequence:
TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP
Storage/Stability:
Store at -20°C to -80°C for 1 year.