Recombinant Human ERK2 GST Tag, Inactive

Synonyms:

Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK

Species:

Human

Cat. No.:

CRE136C pdf (datasheet)

Quantity/Size:

50 μg

Price:

$900.00 BUY

Description:

Recombinant full-length human ERK2 was expressed in E. coli with an N-terminal GST tag.

ERK2 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines. Activation of ERK2 requires both tyrosine and threonine phosphorylation that is mediated by MEK. ERK2 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. Activated ERK2 translocates into the nucleus where it phosphorylates various transcription factors (Elk-1, c-Myc, c-Jun, c-Fos, and C/EBP beta).

Concentration:

0.2 mg/ml

Entrez Symbol:

MAPK1

Uniprot Name:

Mitogen-activated protein kinase 1

Uniprot ID:

P28482

Data PDF:

CRE136

Source:

E. coli

Molecular Weight:

68 kDa

Tag:

GST

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol

Purity:

>90% as determined by SDS-PAGE densitometry

Storage/Stability:

Store at -80°C up to 1 year