Synonyms:
C-C motif chemokine 14, HCC-1 (1-74), Chemokine CC-1/CC-3, Small-inducible cytokine A14, SCYA14
Description:
CCL14 is a CC chemokine that signals through the CCR1 receptor and chemoattracts blood monocytes. It is secreted by various tissues, including skeletal muscle, heart, spleen, liver, bone marrow and plasma. Mature CCL14 is found in four different forms, which are distinguished by differential N-terminal truncation and contain 74, 72, 71, or 66 amino acid residues. Recombinant Human CCL14 is a 7.8 kDa protein consisting of 66 amino acids, including the four highly conserved residues present in CC chemokines.
Molecular Weight:
7.8 kDa (66 aa)
Formulation:
Lyophilized from PBS.
Purity:
> 98% by SDS-PAGE and HPLC analyses
Biological Activity:
Determined by its ability to chemoattract human monocytes using a concentration range of 5 - 20 ng/ml.
Endotoxin Level:
< 1 EU/µg
Amino Acid Sequence:
GPYHPSECCF TYTTYKIPRQ RIMDYYETNS QCSKPGIVFI TKRGHSVCTN PSDKWVQDYI KDMKEN
Storage/Stability:
Stable for 1 year at -20°C to -80°C.
