Recombinant Human Cardiac Troponin C-I-T Complex

Synonyms:

Troponin C, slow skeletal and cardiac muscles, TN-C, Troponin I, cardiac muscle, Cardiac troponin I, Troponin T, cardiac muscle, TnTc, Cardiac muscle troponin T, cTnT

Species:

Human

Cat. No.:

CRT130A pdf (datasheet)

Quantity/Size:

2 μg

Price:

$450.00 BUY

Description:

Troponin Complex is a heteromeric protein playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, Troponin I, Troponin T and Troponin C. Each subunit is responsible for part of Troponin Complex function. E.g. Troponin I inhibits ATP-ase activity of acto-myosin.Troponin T and Troponin I are presented in cardiac muscles in different forms than in skeletal muscles. Purified subunits of rcTnI, rcTnC and rcTnT are recomplexed in vitro under appropriate conditions, with a 1:1:1 molar ratio.

Concentration:

50 µg/ml

Entrez Symbol:

TNNC1, TNNI3, TNNT2

Uniprot ID:

P63316, P19429, P45379

Data PDF:

CRT130

Source:

E. coli

Molecular Weight:

approximately 90 kDa

Formulation:

500 mM NaCl, 20 mM Tris-HCl, 4 mM CaCl2, 4 mM MgCl2, 60 mM 2-mercaptoethanol, pH 7.5

Purity:

> 90% by SDS-PAGE analysis

Storage/Stability:

-20°C to -80°C one year