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Recombinant Human Calreticulin

Synonyms:

Calreticulin, CRP55, Calregulin, Endoplasmic reticulum resident protein 60, ERp60, HACBP, grp60

Species:

Human

Cat. No.:

CRC203 pdf (datasheet)

Quantity/Size:

100 μg

Price:

$1,350.00 BUY

Description:

Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain antiRo/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.

Uniprot Name:

Calreticulin

Uniprot ID:

P27797

Data PDF:

CRC203

Source:

E. coli

Molecular Weight:

46.0 kDa (aa 18-417)

Formulation:

10 mM Tris, 3 mM NaCl, pH 8.0 containing 0.002% sodium azide

Purity:

90% by SDS-PAGE

Storage/Stability:

Store at -80ºC for up to 1 year. Upon initial thaw, store single use aliquots at -80ºC.

Application:

ELISA, MS, WB