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Recombinant Endo S2 / Endo-beta-N-acetylglucosaminidase

Synonyms:

Endo-beta-N-acetylglucosaminidase EndoS2, Endo-S2, Endo S2

Species:

Streptococcus

Cat. No.:

YXX06601A pdf (datasheet)

Quantity/Size:

100 µg

Price:

$420.00 BUY

Description:

Endoglucosidase that acts as a host immune evasion factor by mediating hydrolysis of the N-linked glycan from the Fc region of host immunoglobulin-gamma (IgG) during infection, thereby preventing interaction between IgGs and Fc receptors and ability to activate the complement pathway. Endo S2 recognizes the conserved N-glycans on the Fc region of IgG by hydrolyzing the chitobiose core (at the beta -1,4 linkage between the two N-acetylglucosamines) of the N-glycans.

Entrez Symbol:

endoS2

Uniprot Name:

Endo-beta-N-acetylglucosaminidase EndoS2

Uniprot ID:

T1WGN1

Data PDF:

YXX06601

Source:

E. coli

Molecular Weight:

114.67 kDa, predicted, includes a 23 kDa proprietary tag added to improve solubility.

Formulation:

Lyophilized from PBS pH 7.4, 1 mM EDTA, 4% trehalose,1% mannitol

Purity:

> 90 % as determined by SDS-PAGE.

Storage/Stability:

Store at -80°C up to 1 year

Application notes:

Endo S2 hydrolyzes N-linked glycans on IgG and a1-acid glycoprotein