Choriogonadotropin subunit beta 3, beta hCG, Choriogonadotropin subunit beta, Chorionic gonadotropin chain beta, CG-beta

Human

CS573B pdf (datasheet)

1.0 mg

$3,800.00 BUY

Human chorionic gonadotropin is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Increased levels of beta hCG indicates an implanted blastocyst and mammalian embryogenesis. Human chorionic gonadotropin can be used as a tumor marker as the β subunit is secreted by some cancers including seminoma, choriocarcinoma, germ cell tumors, hydatidiform mole, teratoma with elements of choriocarcinoma, and islet cell tumor. For this reason, a positive result in males can be a test for testicular cancer.

CGB3

Choriogonadotropin subunit beta 3

P0DN86

CS573

E. coli

17.9 kDa (168 aa) monomer

Sterile filtered 20 mM Tris-HCl, pH 8.0 containing 0.4 M urea and 10% glycerol

> 85% as determined by SDS-PAGE

MGSSHHHHHH SSGLVPRGSH MGSSKEPLRP RCRPINATLA VEKEGCPVCI TVNTTICAGY CPTMTRVLQG VLPALPQVVC NYRDVRFESI RLPGCPRGVN PVVSYAVALS CQCALCRRST TDCGGPKDHP LTCDDPRFQD SSSSKAPPPS LPSPSRLPGP SDTPILPQ.

Store at 2-8°C for use within 2 weeks. Store unopened at -20°C to -80°C for up to 1 year. It is recommended to store at -20°C to -80°C in aliquots with added carrier protein (0.1% HSA or BSA). Avoid repeated freeze-thaw cycles.