Nectin-2, Herpes virus entry mediator B, Poliovirus receptor-related protein 2, Nectin cell adhesion molecule 2, CD112

Mouse

MON2092 pdf (datasheet)

100 µg

$1,480.00 BUY

0.1 mg/ml

Nectin (originally isolated as poliovirus receptor-related protein (PRR)) is a cell-cell adhesion molecule of the immunoglobulin supergene family. Nectin is colocalized with afadin at cadherin-based cell-cell adherence junctions in various tissues and cell lines. The nectin family consist of nectin-1, nectin-2 and nectin-3. Nectin-2 also known as PRR2 or CD112 is a plasma membrane adhesion molecule localized at adherens junctions which is widely expressed in various cell lines including neuronal, endothelial, epithelial and hematopoietic cells. Next to its role in adherens junctions it functions as alphaherpus virus receptor and acts also as intercellular adhesion molecule and pseudorabies virus receptor. Disruption of mouse nectin-2 leads to infertility of male mice.. The antibody cross reacts with human nectin-2.

Nectin2

P32507

MON2092

Mouse Nectin-2

Rat

Extracellular domain of mouse nectin-2

IgG2a

502-57

Purified antibody in PBS containing 0.1% bovine serum albumin and 0.02% sodium azide

1200

ELISA, FC, IHC, IP , WB

Stable for at least one year at 2-8°C.