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Rat Anti-Mouse IFN-alpha (Clone F18) Neutralizing mAb

Synonyms:

Interferon alpha-1, IFN-alpha-1, IFN-a

Species:

Mouse

Cat. No.:

MON5067 pdf (datasheet)

Quantity/Size:

1.0 ml

Price:

$900.00 BUY

Concentration:

100 µg/ml

Description:

Rat monoclonal anti-mouse IFN-alpha (clone F18) binds and neutralizes both native and recombinant mouse alpha Interferon. It may be used for biological assays as well as for purification. The antibody reacts with most isoforms of native or recombinant mouse alpha interferons. It does not cross react with mouse Interferons beta or gamma, nor with human Interferons. With the availability of monoclonal antibodies directed against alpha Interferon, it is possible to interpret results obtained from crude materials containing both alpha and beta Interferon. The difficulties in studying in vitro and in vivo effects of Type 1 Interferons arise from the fact that both alpha and beta Interferons are produced in response to the same stimuli and also seem to act via the same receptor. These Interferon activities can only be distinguished from one another by use of specific neutralizing antibodies.

Entrez Symbol:

Ifna1

Uniprot Name:

Interferon alpha-1

Uniprot ID:

P01572

Data PDF:

MON5067

Specificity:

Native and recombinant mouse IFN-alpha

Host Species:

Rat

Isotype:

IgG1

Clone:

F18

Formulation:

Sterile-filtered PBS containing 0.02% sodium azide and 0.1% BSA

Application:

ELISA, FC, Functional assay, Neutralizing , WB

Storage/Stability:

Store at 2-8°C for up to 1 year