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Stage-specific embryonic antigen-4 (SSEA-4) is a ganglioside which consists of a glycosphingolipid (GSL) containing a terminal sialic acid residue (N-acetylneuraminic acid). SSEA-4 expression changes both qualitatively and quantitatively during development, differentiation and in tumorigenesis. SSEA-4 has been found to be over-expressed in a number of cancers and has been correlated with disease progression.
Rabbit Anti-Human SSEA-4 (Clone E2-F8) mAb is a high affinity IgG1 recombinant rabbit monoclonal antibody to Stage-Specific Embryonic Antigen-4 (SSEA-4).