Native Human Transferrin (HOLO), Plasma, Cell Culture Grade

Synonyms:

Serotransferrin, Beta-1 metal-binding globulin

Species:

Human

Cat. No.:

CSI19828B pdf (datasheet)

Quantity/Size:

1 g

Price:

$750.00 BUY

Description:

Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100 ml. The Holo form of transferrin is iron saturated. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and prevention of iron loss via the kidneys. Stored in bone marrow as Tf-bound iron, it also possesses bacteriostatic and fungistatic activity. It is an important transport factor used in defined culture media. Clinically, decreases in transferrin are observed in congenital disorders, newborns, inflammatory diseases, hypoproteinemias and nephrotic syndrome; increases are found in pregnancy, iron-deficiency anemias, and inoculation hepatitis. Transferrin is required by all types of cells in cultures for maximal growth.
This product is tested in cell culture and shown to be free of toxins and other contaminants which could inhibit cultured cell growth.

Entrez Symbol:

TF

Uniprot Name:

Serotransferrin

Uniprot ID:

P02787

Data PDF:

CSI19828

Source:

Human plasma

Molecular Weight:

80 kDa

Formulation:

Lyophilized from sterile-filtered 20 mM sodium phosphate, 150 mM NaCl, pH 7.4

Purity:

> 95% by SDS-PAGE analysis

Endotoxin Level:

< 1 EU/mg by LAL analysis

Reconstitution:

Add sterile distilled water to prepare a 1-3% solution.

Storage/Stability:

Store at -20°C to 80°C for at least 1 year

Application notes:

Iron content: > 1100 mg per gram (saturated, diferric transferrin, HOLO)