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Native Human Thyroid Stimulating Hormone Intact High Purity

Molecule:

TSH

Synonyms:

Thyrotropic Hormone, Thyrotrophin, Thyrotropin, TSH, TTH, TSH-A, TSH-B

Species:

Human

Cat. No.:

CRT504-1000 pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$4,750.00 BUY

Description:

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical (CGA), however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The beta subunit of thyroid stimulating hormone is encoded by the gene TSHB.

Entrez Symbol:

CGA, TSHB

Uniprot Name:

Glycoprotein hormones alpha chain, Thyrotropin subunit beta

Uniprot ID:

P01215, P01222

Data PDF:

CRT504

Source:

Human pituitary

Molecular Weight:

28 kDa

Formulation:

Lyophilized from a solution in 50 mM Ammonium Bicarbonate

Purity:

≥98% by SDS-PAGE

Specific Activity:

> 5 IU/mg, by Accubind ELISA (calibrated to the WHO 2nd IRP 80/558 )

Reconstitution:

Centrifuge vial prior to opening. Reconstitute using neutral pH buffer of choice. Avoid extreme high and low pH.

Storage/Stability:

Upon receipt, store as supplied at 2-8 °C. After reconstitution, store in working aliquots at -20 °C to -80 °C for up to one year. Avoid repeated freeze-thaw cycles.