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An acute-phase plasma protein found at 45 mg per 100 ml. Anti-chymotrypsin (ACT) functions as a specific inhibitor of chymotrypsin-like serine proteases. Clinically, it is elevated in inflammatory conditions, some malignancies, Crohn's disease, ulcerative colitis, and burn injuries. The PSA-ACT complex level is considered a biomarker for prostate cancer.