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Native Human Kallikrein, Plasma

Synonyms:

Plasma kallikrein, Fletcher factor, Kininogenin, Plasma prekallikrein (PKK)

Species:

Human

Cat. No.:

CSI19814A pdf (datasheet)

Quantity/Size:

50 ug

Price:

$400.00 BUY

Description:

A serine protease that cleaves Lys-Arg and Arg-Ser bonds in kininogen to release bradykinin. Present in plasma as an inactive precursor prekallikrein, cleaved by Factor XII. Plasma kallikrein liberates kinins (bradykinin and kallidin) from the kininogens, peptides responsible for the regulation of blood pressure and activation of inflammation. It is also capable of generating plasmin from plasminogen.

Concentration:

Lot specific

Uniprot Name:

Plasma kallikrein

Uniprot ID:

P03952

Data PDF:

CSI19814

Source:

Human plasma

Molecular Weight:

86-88 kDa

Formulation:

20 mM Tris-HCl, 100 mM NaCl, pH 7.8

Purity:

> 95% by SDS-PAGE analysis

Biological Activity:

One unit is defined as the amount of enzyme that hydrolyzes one umole of D-Pro-PheArg-pNA per minute at 25°C, pH 7.8.

Specific Activity:

15 units/mg

Storage/Stability:

Store at -80°C for up to 1 year.