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Native Human Platelet Factor 4

Synonyms:

Platelet factor 4, PF-4, C-X-C motif chemokine 4, Iroplact, Oncostatin-A

Species:

Human

Cat. No.:

CRP139B pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$2,700.00 BUY

Description:

Platelet Factor 4 is synthesized in megakaryocytes and platelets. Depending on the protein concentration and buffer conditions, PF4 appears as a mono-, di-, tri-, or tetramer. PF4 is biologically active in the tetrameric form, promotes blood coagulation and is also important in wound healing and inflammation. PF4, together with heparin (PF4-heparin complex) is an important antigen of antibodies inducing heparin-induced thrombocytopenia (HIT). Purified PF4 is used in several laboratory tests for the detection of HIT antibodies.

Entrez Symbol:

PF4

Uniprot Name:

Platelet factor 4

Uniprot ID:

P02776

Data PDF:

CRP139

Source:

Human blood

Molecular Weight:

7.8 kDa (70 aa) monomer, 31.2 kDa tetramer

Formulation:

Lyophilized from sterile filtered PBS carrier free (HBSS or 1.6 M NaCl, available by request)

Purity:

> 98% as determined by SDS-PAGE with silver staining

Storage/Stability:

Store unopened at -20°C to -80°C