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Native Human Lipoprotein(a), Plasma

Synonyms:

Lipoprotein(a), Lp(a), LPA, Apolipoprotein(a), Apo(a)

Species:

Human

Cat. No.:

CRA169B pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$2,000.00 BUY

Description:

Lipoprotein(a) [Lp(a)] consists of an LDL-like particle and the specific apolipoprotein(a). Lp(a) plasma concentrations are highly heritable, thus in different ethnic groups, different genetic alterations were associated with increased Lp(a) levels. Lp(a) contributes to the process of atherogenesis. The structure of apolipoprotein(a) is similar to plasminogen and tPA (tissue plasminogen activator) and it competes with plasminogen for its binding site, leading to reduced fibrinolysis. Also, because Lp(a) stimulates secretion of PAI-1, it leads to thrombogenesis. Elevated Lp(a) correlates with coronary heart disease (CHD), cardiovascular disease (CVD), atherosclerosis, thrombosis, and stroke.

Concentration:

1.0 mg/ml, lot specific, based on Diazyme Lp(a) Assay

Entrez Symbol:

LPA

Uniprot Name:

Lipoprotein(a)

Uniprot ID:

P08519

Data PDF:

CRA169

Source:

Human plasma

Molecular Weight:

280-700 kDa

Formulation:

20mM Tris, 90mM NaCl, 0.1M L-Proline, 0.05% NaN3, pH 8.2
Note: formulation change for improved stability.

Purity:

>95% by SDS-PAGE analysis, minor Apolipoprotein A1 contaminant.

Storage/Stability:

Stable at 2-8°C. DO NOT FREEZE.