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Native Human Coagulation Factor XIII

Molecule:

Factor XIII

Synonyms:

Coagulation factor XIII A chain, F13A, F13A1, and Coagulation factor XIII B chain, FXIIIB, F13B

Species:

Human

Cat. No.:

CSI20179A pdf (datasheet)

Quantity/Size:

250 μg

Price:

$1,070.00 BUY

Description:

Human Factor XIII is a tetramer composed of two pairs of chains held together by noncovalent bonds. After activation of the zymogen via Thrombin to its active enzyme form, activated Factor XIIIa is responsible for catalyzing the formation of covalent bridges between fibrin units to increase the elasticity of the clot network. The resulting cross-linked fibrin is very insoluble and resistant to lysis.

Concentration:

> 1.0 mg/ml, lot specific

Entrez Symbol:

F13A1, F13B

Uniprot Name:

Coagulation factor XIII

Uniprot ID:

P00488 A chain, P05160 B chain

Data PDF:

CSI20179

Source:

Human plasma

Molecular Weight:

320 kDa

Physical State:

Frozen liquid

Formulation:

50 mM Tris-HCl, 0.1 M NaCl, 1 mM EDTA, 10 U/ml Aprotinin, 20% Glycerol , pH 7.5

Purity:

>95% by SDS-PAGE analysis

Biological Activity:

> 2300 Loewy units/mg (one plasma equivalent unit (PEU) is equal to approximately 108 Loewy units)

Storage/Stability:

Store at -80°C for up to 1 year.