• Home /
  • Native Human Apolipoprotein B

Native Human Apolipoprotein B

Synonyms:

LDL protein, Low Density lipoprotein protein, Apolipoprotein B protein, Apo-B protein, Apo B protein

Cat. No.:

CRA128 pdf (datasheet)

Quantity/Size:

0.5 mg

Price:

$450.00 BUY

Description:

Apolipoprotein B is the dominant protein constituent of LDL. The concentration of Apo B in normal plasma is 90 mg per 100 ml. Apo B is thought to stabilize lipid emulsions, serve as a cofactor and modulator of enzymatic reactions, manage export of lipids out of cells and direct lipids to target organs. In a normal fasting individual, low density lipoprotein concentrations range from 2.0 - 3.5 g/L. LDL constitutes 50% of the total lipoprotein mass in plasma and is the major carrier of cholesterol and cholesteryl esters. LDL levels strongly correlate with coronary heart disease.

Concentration:

~2.0 mg/ml, lot specific, modified Lowry procedure, prior to lyophilization

Uniprot Name:

Apolipoprotein B-100

Uniprot ID:

P04114

Data PDF:

CRA128

Source:

Human plasma

Molecular Weight:

550 kDa

Formulation:

Lyophilized from 10 mM sodium deoxycholate, pH 10.0, with 50 mM Na2CO3 and 50 mM NaCl

Purity:

≥95% pure by SDS-PAGE, single arc by IEP against whole human serum

Reconstitution:

Centrifuge briefly to ensure complete recovery. Add de-ionized H2O to the original volume followed by gentle vortexing/swirling for homogenization.

Storage/Stability:

Upon receipt, store at -20o C. Upon reconstitution store at 2-8 o C for up to 1 week, or prepare aliquots and store at -20o C to -80o C. Avoid repeated freeze/thaw cycles.