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Native Human Antithrombin-III

Synonyms:

Antithrombin-III, ATIII, Serpin C1

Species:

Human

Cat. No.:

CRA162B pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$450.00 BUY

Description:

Human Antithrombin III is an important small molecule serine protease inhibitor that inactivates several enzymes of the coagulation system, thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa . Human Antithrombin is a glycoprotein produced by the liver and a member of a larger family of antithrombins (numbered I, II etc. to VI), all of which are serpins. Potency is strongly enhanced by heparin. Clinically, reduced levels are indicative of hypercoagulability. Antithrombin III is found in normal serum at 15 mg per 100 ml. Higher levels in plasma vs. serum because of complexing with thrombin during coagulation.

Entrez Symbol:

SERPINC1

Uniprot Name:

Antithrombin-III

Uniprot ID:

P01008

Data PDF:

CRA162

Source:

Human plasma

Molecular Weight:

58.0 kDa

Formulation:

Lyophilized from 50 mM Tris-HCl, pH 8.0 with 150 mM sodium chloride.

Purity:

≥ 95% (SDS-PAGE)

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1-1.0 mg/mL and gently pipette the solution up and down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution.

Storage/Stability:

Store lyophilized protein at -20 to -80°C for 1 year.