Native Human Alpha-2-Macroglobulin

Molecule:

Alpha-2-Macroglobulin

Synonyms:

Alpha-2-macroglobulin, Alpha-2-M, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5

Species:

Human

Cat. No.:

CRA115C pdf (datasheet)

Quantity/Size:

10 mg

Description:

A major serum protein found at concentrations of 240 mg per 100 ml in men and 290 mg per 100 ml in women. Multifunctional, it promotes growth of mammalian cells in culture, stimulates the regeneration of lymphocytes in irradiated mice, possesses a transport function for zinc and is a protease inhibitor that controls the clotting and fibrinolytic system. Clinically levels are increased in liver cirrhosis, nephrotic syndrome, diabetes, and severe burn cases.

Entrez Symbol:

A2M

Uniprot Name:

Alpha-2-macroglobulin

Uniprot ID:

P01023

Data PDF:

CRA115

Source:

Human plasma

Molecular Weight:

725 kDa (180 MW subunits) homotetramer

Formulation:

Lyophilized from 30 mM Sodium Phosphate, pH 7.0 containing glycine as a stabilizer

Purity:

>95% pure by SDS-PAGE.

Reconstitution:

Centrifuge vial prior to opening. Prepare the original volume with deionized water.

Storage/Stability:

Stable at 2-8°C for shipping. Store at -80°C for up to 1 year.