Human

MON4009 pdf (datasheet)

100 µg

$830.00 BUY

1.0 mg/ml

MON4009 recognizes a defined epitope (aa 65-97) on N-terminal structural domain of alpha-tubulin. The alpha-tubulin (relative molecular weight about 50 kDa) is globular protein that exists in cells as part of soluble alpha/beta-tubulin dimer or it is polymerized into microtubules. In different species it is coded by multiple tubulin genes that form tubulin classes (in human 6 genes). Expressed tubulin genes are named tubulin isotypes. Some of the tubulin isotypes are expressed ubiquitously, while some have more restricted tissue expression. Alpha-tubulin is also subject of numerous post-translational modifications. Tubulin isotypes and their posttranslational modifications are responsible for multiple tubulin charge variants - tubulin isoforms. Heterogeneity of alpha-tubulin is concentrated in C-terminal structural domain.

MON4009

Alpha-Tubulin

Mouse

Fraction of tubulin purified from porcine brain by two cycles of polymerization - depolymerization

IgG1

TU-01

PBS containing 15 mM sodium azide

ICC, IHC-P, IP , WB

Store at 2-8°C for up to 1 year.