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Mouse Anti-Phospho-Tau (pS396/pS404) (SAA0294) mAb

Synonyms:

Microtubule-associated protein tau, TAU, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, MAPTL, MTBT1

Cat. No.:

RHC82407A pdf (datasheet)

Quantity/Size:

100µg

Price:

$485.00 BUY

Concentration:

1.0 mg/ml, lot specific

Description:

Tau protein is a microtubule-associated protein, predominantly expressed in the neurons, closely associated with the proper functioning of the cytoskeletal network in terms of microtubule assembly. Tau protein in the CSF is considered as an important biomarker of several disorders of the CNS where axonal damage is contemplated. In Alzheimer disease, the neuronal cytoskeleton in the brain is progressively disrupted and replaced by tangles of paired helical filaments (PHF) and straight filaments, mainly composed of hyperphosphorylated forms of TAU (PHF-TAU or AD P-TAU).

Entrez Symbol:

MAPT

Uniprot Name:

Microtubule-associated protein tau

Uniprot ID:

P10636

Purity:

> 95% by SDS-PAGE

Host Species:

Mouse

Isotype:

IgG2a kappa light chain

Clone:

SAA0294

Formulation:

0.01M PBS buffer, pH 7.4

Purification:

Protein A or G affinity chromatography from cell culture supernatant

Application:

IHC, IP , WB

Storage/Stability:

Store at -20°C to -80°C for up to 1 year.