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  • Mouse Anti-Human VEGFR-2/KDR (Clone #EIC) FITC mAb

Mouse Anti-Human VEGFR-2/KDR (Clone #EIC) FITC mAb

Molecule:

VEGFR-2/KDR

Synonyms:

Vascular endothelial growth factor receptor 2, VEGFR-2, Kinase insert domain receptor, KDR, Fetal liver kinase 1, FLK-1, CD309

Species:

Human

Cat. No.:

CMV002FITC pdf (datasheet)

Quantity/Size:

50 μg

Price:

Please Inquire

Description:

VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

Entrez Symbol:

KDR

Uniprot Name:

Vascular endothelial growth factor receptor 2

Uniprot ID:

P35968

Data PDF:

CMV002-FITC

Specificity:

Human VEGFR-2

Host Species:

Mouse

Immunogen:

Recombinant human soluble extracellular KDR (110 kDa)

Isotype:

IgG1

Clone:

#EIC

Conjugate:

FITC

Formulation:

PBS, containing 1% BSA and 0.02% sodium azide

Purification:

Protein G Chromatography

Application:

FC

Application notes:

FACS:  use at 2-10 µg/ml 

Storage/Stability:

Store protected from light at 2-8°C. Do not freeze!