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Mouse Anti-Human VEGFR-2/KDR Clone #3(4H3) mAb

Molecule:

VEGFR-2/KDR

Synonyms:

FLK1, CD309, VEGFR, VEGFR2

Species:

Human

Cat. No.:

CMV012 pdf (datasheet)

Quantity/Size:

100 μg

Price:

$570.00 BUY

Description:

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. VEGF recptor 2 is one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signaling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, and T-cell protein tyrosine phosphatase.

Data PDF:

CMV012

Specificity:

Detects Native Human KDR/VEGFR-2 on the surface of different human cell types.

Host Species:

Mouse

Immunogen:

Recombinant Human soluble extracellular KDR (D7)

Isotype:

IgG1

Clone:

#3(4H3)

Formulation:

Lyophilized from PBS, pH 7.2 without preservative.

Purification:

Protein G chromatography

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water for a concentration of 0.1 -1.0 mg/ml.

Application notes:

Western blot: suggested concentration 2-5 μg/ml
FACS: suggested concentration 2-5 μg/ml.

Optimal dilution should be determined by each laboratory for each application.

Storage/Stability:

Store lyophilized at -20°C for up to 1 year. Following reconstitution, stable for at least two weeks at 2-8°C or at least 6 months when stored at -20°C. Avoid repeated freeze-thaw cycles.