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Mouse Anti-Human TNF-alpha Clone T1 mAb

Synonyms:

Tumor necrosis factor, Cachetin, TNF-a

Species:

Human

Cat. No.:

MON9068 pdf (datasheet)

Quantity/Size:

100 μg

Price:

$960.00 BUY

Concentration:

0.1 mg/ml

Description:

Mouse Anti-Human TNF-alpha Clone T1 mAb

Uniprot Name:

Tumor necrosis factor

Uniprot ID:

P01375

Data PDF:

MON9068

Specificity:

Reacts with free soluble (17 kDa) and membrane (26 kDa) human TNF-α.

Host Species:

Mouse

Immunogen:

Recombinant human TNF-alpha

Isotype:

IgG1

Clone:

T1

Formulation:

Sterile-filtered PBS, containing 0.02% sodium azide and 0.1% bovine serum albumin. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.

Application:

ELISA, FC, FS , INH, IP , WB

Application notes:

The antibody inhibits the biological activity of both forms. It does not react with receptor bound TNF-α. It can be a useful tool to discriminate between the membrane form of TNF expressed on producer cells and the proteolytically cleaved, soluble TNF-α bound to its cognate cell membrane receptors (TNF-RI and TNF-RII). For this purpose we recommend to use this antibody in combination with the anti-TNF-α antibody MON9067, which recognizes soluble, membrane and receptor bound TNF-α.

Storage/Stability:

Store at 2-8°C