4F2 cell-surface antigen heavy chain, 4F2 heavy chain antigen, 4F2hc, Lymphocyte activation antigen 4F2 large subunit, Solute carrier family 3 member 2, CD98

Human

MON1070 pdf (datasheet)

100 μg

$750.00 BUY

1.0 mg/ml

Mouse Anti-Human SLC7A5/CD98 Clone MEM-108 reacts with CD98, a 125 kDa disulfide-linked heterodimer (80 kDa glycosylated heavy chain + 45 kDa non-glykosylated light chain). CD98 is expressed on T lymphocytes (upon activation) and activated NK cells; it is also present at low levels on B lymphocytes, NK cells, monocytes and platelets. CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98,linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation.

4F2 cell-surface antigen heavy chain

P08195

MON1070

This antibody reacts with the CD98 antigen

Mouse

RAJI human Burkitt's lymphoma cell line

IgG1

MEM-108

PBS, 15 mM sodium azide, pH 7.4.

FC, IHC-P, IP

Flow Cytometry: recommended concentration 4 µg/ml

IHC-parafin: recommended concentration 10 µg/ml

Immunoprecipitation: recommended concentration to be determined

The optimal working dilution should be determined for each application.

Store undiluted antibody at 2-8°C for up to 1 year.