Mouse Anti-Human / Mouse ROR1 (R11) mAb , APC

Synonyms:

Inactive tyrosine-protein kinase transmembrane receptor ROR1, mROR1, Neurotrophic tyrosine kinase, receptor-related 1

Species:

Human

Cat. No.:

FMF90713B pdf (datasheet)

Quantity/Size:

100 T

Price:

$585.00 BUY

Concentration:

0.5 mg/ml, lot specific

Description:

Receptor tyrosine kinase ROR1 plays an essential role in embryogenesis and is overexpressed in many types of malignant tumors. Studies have demonstrated that in oncogenesis ROR1 activates cell survival signaling events, particularly the non-canonical WNT signaling pathway. Antibody-based immunotherapies targeting ROR1 show promise in certain malignancies. Allophycocyanin labeled monoclonal antibody R11 binds with Mouse and Human ROR1.

Entrez Symbol:

ROR1

Uniprot Name:

Inactive tyrosine-protein kinase transmembrane receptor ROR1

Uniprot ID:

Q01973 and Q9Z139

Purity:

> 95% by SDS-PAGE

Specificity:

Human and Mouse ROR1

Host Species:

Mouse

Isotype:

IgG2a kappa light chain

Clone:

R11

Formulation:

0.01M PBS buffer, pH 7.4, 0.2% BSA, 0.05% Proclin 300

Purification:

Protein A/G affinity chromatography from cell culture supernatant

Application:

FC

Storage/Stability:

Store at 2-8°C for up to 1 year. Protect from light. Do not freeze.